EurekaMag.com logo
+ Site Statistics
References:
52,725,316
Abstracts:
28,411,598
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Epidemiological trial of the prophylactic effectiveness of dipyridamole the interferon inducing agent with respect to influenza and acute respiratory diseases


Zhurnal Mikrobiologii Epidemiologii i Immunobiologii (6): 26-30
Epidemiological trial of the prophylactic effectiveness of dipyridamole the interferon inducing agent with respect to influenza and acute respiratory diseases
The epidemiological effectiveness of dipyridamole and interferon-inducing agent used for the prevention of influenza and viral acute respiratory diseases, was tested in 4 epidemiological trials, 3 of them carried out as double blind trials. Observations were made in groups of adults (a research institute, a factory) and children (a kindergarten, a school), comprising 1040 subjects in the test groups and 771 subjects in the control groups. The drug was used during the whole epidemic period (January-March 1983) according to the following schedule: 1 oral administration in 8 days, in doses of 8 mg for adults, 50 mg for schoolchildren and 24 mg for children in the kindergarten. The epidemiological effectiveness of the drug was evaluated by comparing the total morbidity rates in influenza and acute respiratory diseases in the test and control groups. The results of 4 trials showed a pronounced epidemiological effectiveness of dipyridamole. The values of the epidemiological effectiveness index of the drug were 2.38 in the kindergarten, 1.55 at the school, 7.42 at the factory and 2.16 at the research institute. The results of the study of dipyridamole suggest that further investigations should be made with a view to use it for the mass prevention of influenza and acute respiratory diseases.


Accession: 005375725



Related references

Epidemiological trial of the prophylactic effectiveness of the interferon inducer dipyridamole with respect to influenza and acute respiratory diseases. Zhurnal Mikrobiologii, Epidemiologii, i Immunobiologii: 26-30, 1985

Human leukocytic interferon as an agent for emergency prevention of influenza and other acute respiratory diseases in children's preschool institutions. Pediatriia: 74-78, 1990

Evaluation of dipyridamole efficacy as an agent for preventing acute respiratory viral diseases. Voprosy Virusologii 32(3): 294-297, 1987

Evaluation of the effectiveness of dipyridamole as a means for the prevention of acute respiratory diseases. Voprosy Virusologii 32(3): 294-297, 1987

Prophylaxis of influenza and other acute respiratory diseases of children by leukocytal interferon and interferon inducers uf virus. Voprosy Virusologii 16(4): 442-446, 1971

Prevention of influenza and other acute respiratory diseases in children with leukocyte interferon and a stimulator interferon formation (UF virus). Voprosy Virusologii 16(4): 442-446, 1971

Epidemiological aspects of acute respiratory diseases including influenza. Industrial Medicine & Surgery 27(10): 498-499, 1958

The Respiratory Protection Effectiveness Clinical Trial (ResPECT): a cluster-randomized comparison of respirator and medical mask effectiveness against respiratory infections in healthcare personnel. Bmc Infectious Diseases 16(): 243-243, 2016

Epidemiological and economic effectiveness of immunization of adults and children against influenza and acute respiratory viral infections with the vaccine Grippol. Zhurnal Mikrobiologii Epidemiologii i Immunobiologii (3): 83-86, May-June, 2003

Epidemiological and economic effectiveness of immunization of adult and children against influenza and acute respiratory viral infections with the vaccine Grippol. Zhurnal Mikrobiologii, Epidemiologii, i Immunobiologii: 83-86, 2003