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Epidemiology and mass treatment of ascariasis in 6 rural communities in central iran


American Journal of Tropical Medicine and Hygiene 26((5 PART 1)): 866-871
Epidemiology and mass treatment of ascariasis in 6 rural communities in central iran
In 6 villages near Isfahan in central Iran 1455 persons were examined for intestinal parasites. Those with Ascaris infection were treated with pyrantel pamoate in a single dose of 10 mg/kg body wt and all stools passed during 48 h after treatment were collected in plastic pans and screened for worms which were then sexed and measured. Ascaris infection rates, 87-95% in the 6 villages before treatment, were reduced to 1-8% (average 5%) and the mean number of eggs in the feces was reduced from 19/mg to < 1/mg. All age groups and both sexes were about equally infected, and the average number of worms expelled by treatment ranged from 16/infected person below 5 yr of age to 31/person 20-39 yr of age. Mature and immature worms together were expelled from persons treated at all seasons, indicating that worms were acquired and lost continuously throughout the year. Fecal examination at 2, 4, 6 and 12 mo. after treatment showed that the prevalence at 12 mo. returned to the original level (87% vs. 91%) but the average intensity as reflected in egg-counts had not (10 vs. 19/mg feces). The findings confirm the necessity of repeated treatments at 2-3 mo. intervals.

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Accession: 005375802



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