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Equine laminitis 3. coagulation dys function in the developmental and acute disease



Equine laminitis 3. coagulation dys function in the developmental and acute disease



Journal of Equine Medicine and Surgery 3(8): 355-360



The hypothesis that disseminated intravascular coagulation (DIC) is a pathophysiologic mechanism in equine laminitis was investigated in 9 horses. Carbohydrate overload was used to induce acute laminitis. Prothrombin times in these horses demonstrated no significant changes. Activated partial thromboplastin times, platelet numbers and fibrin split product titers demonstrated fluctuations which were consistent with periodic episodes of clotting dysfunction. These episodes preceded lameness by .apprxeq. 1 h. DIC apparently is involved primarily or secondarily in the laminitis syndrome.

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Accession: 005380144

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