+ Site Statistics
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Evaluation of a continuous estrogen progestogen regimen for climacteric complaints

Maturitas 4(2): 95-102

Evaluation of a continuous estrogen progestogen regimen for climacteric complaints

Subjective complaints, endometrial histopathology, vaginal cytology and bleeding patterns were recorded in 26 patients treated with a continuous estrogen-progestogen regimen for 12 mo. A marked reduction of hot flushes and sweats were noted and the evaluation of endometrial specimens revealed that the mucosae were mostly inactive-atrophic. The karyopyknotic index proved to be a poor indicator of estrogenic activity. The number of recorded bleedings in the peri-menopausal women differed markedly from the post-menopausal women during treatment; they were very slight in the latter group. Even in those cases where bleeding occurred, the endometrial samples were atrophic. Vaginal bleeding seemed to be an unreliable indicator of endometrial histopathology. The present combination of hormones used in a continuous regimen is a good alternative for post-menopausal women in need of hormonal therapy.

(PDF 0-2 workdays service: $29.90)

Accession: 005395027

PMID: 7121296

Related references

A continuous estrogen-progestogen regimen for climacteric complaints. Effects on lipid and lipoprotein metabolism. Acta Obstetricia et Gynecologica Scandinavica 63(8): 673-677, 1984

Endometrial effects of a continuous percutaneous estrogen low dose oral progestogen regimen for climacteric complaints. Maturitas 9(1): 63-68, 1987

Four different regimens of continuous estrogen progestogen for climacteric complaints. Archives of Gynecology 237(SUPPL): 211, 1985

Estrogen-progestogen replacement in climacteric women, particularly as regards a new type of continuous regimen. Acta Obstetricia et Gynecologica Scandinavica. Supplement 130: 53-58, 1985

The relative fatty acid composition of serum lecithin and cholesterol ester: influence of an estrogen-progestogen regimen in climacteric women. American Journal of Obstetrics and Gynecology 155(1): 174-177, 1986

Comparison of continuous and sequential estrogen progestogen treatment in women with climacteric symptoms. Maturitas 11(1): 75-82, 1989

Effects of a continuous estrogen progestogen therapy for climacteric symptoms on circulating sex steroids and gonadotropins. Archives of Gynecology 233(2): 101-108, 1983

Lipid metabolic and hormonal effects of a continuous estrogen progestogen regimen. Acta Obstetricia et Gynecologica Scandinavica Supplement (116): 74-75, 1983

Comparison of four continuously administered progestogen plus estradiol combinations for climacteric complaints. British Journal of Obstetrics & Gynaecology 95(10): 1042-1048, 1988

Tibolone versus conjugated estrogens and sequential progestogen in the treatment of climacteric complaints. Maturitas 23(1): 55-62, 1996