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Evaluation of a new diagnostic kit for enzymatic determination of creatinine

, : Evaluation of a new diagnostic kit for enzymatic determination of creatinine. Journal of Clinical Chemistry & Clinical Biochemistry 17(10): 633-638

A new diagnostic kit for the enzymatic determination of creatinine in serum, plasma and urine was evaluated. The method was linear up to 1000 .mu.mol/l. Within-run precision had a coefficient of variation of 3.1-5.6% for normal to slightly elevated values and of 2.3-3.3% for values of about 320 .mu.mol/l. Day-to-day precision was 7.8 and 5.7% for values of 94 and 141 .mu.mol/l, respectively. Mean analytic recovery was 98%. Bilirubin and Hb did not interfere in concentrations up to 490 and 240 .mu.mol/l, respectively. The influence of lipids was studied. Correlation studies were done with 2 other methods, the Technicon SMA 12/60 method and the Dutch standard manual method.

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