EurekaMag.com logo
+ Translate

Evaluation of a new fecal occult blood testing


, : Evaluation of a new fecal occult blood testing. Journal of Kyoto Prefectural University of Medicine 95(10): 1331-1338

The incidence of colorectal cancer is increasing in Japanese, and several trials for its early detection have been conducted. Fecal occult blood testing has been proved to be useful in the mass screening of colorectal cancer. New methods based on immunological reaction have recently been developed, which exclusively detect human hemoglobin in the stool. In this paper, we evaluated the usefulness of the new fecal occult blood testing (OC-Hemodia-Eiken), which is based on latex agglutination reaction, in the detection of colorectal cancer. Three days consecutive testing was carried out in 30 cases with colorectal cancer, 35 cases with colorectal polyp, 8 cases with gastric cancer and 137 normal subjects. Positive results were obtained in 100% of colorectal cancer, 42.9% of colorectal polyp and 37.5% of gastric cancer. False positive ratio in the normal subjects was low (5.1%). These data show that the new method is superior in both sensitivity and specificity to other immunological fecal occult blood tests using enzyme immunoassay. While other immunological tests are technically complicated, this new test is rather easy and time-sparing. Considering these advantages, OC-Hemodia-Eiken is expected to be useful in the mass screening of colorectal cancer.

(PDF 0-2 workdays service)

Accession: 005395371

Submit PDF Full Text: Here


Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:
Close
Close

Related references

Schellenberger, U.; Raabe, A.; Erler, K., 1987: Screening test for colorectal cancer. Practical experiences with fecal testing for occult blood. 1: Positive predictive value of occult blood testing. Zeitschrift für Arztliche Fortbildung 81(19): 1007-1009

Fleisher M.; Schwartz M.K.; Winawer S.J., 1980: Laboratory evaluation of products for fecal occult blood testing. Gastroenterology 78(5 PART 2): 1165

Kim, J.Hyun.; Chung, H-Jung.; Yoon, N.Surp.; Pyo, Y.Jeong.; Bae, H.Gyung.; Kim, M-Na., 2007: Evaluation of the OC-SENSOR neo system for testing fecal occult blood. Fecal occult blood tests (FOBTs) have been widely used as a means of colorectal cancer screening. Automated FOBTs using immunologic principles have the advantages such as quantitation, high specificity, and high throughput. We evaluated a newly-in...

Nishikawa, A.; Okuda, T.; Kubota, I.; Azuma, H.; Tanaka, T.; Koyasu, T.; Kumazaki, N.; Iwata, H.; Tanaka, T.; Kato, K., 1987: An evaluation of fecal occult blood screening in automated multiphasic health testing and services. In the present paper, the efficacy of fetal occult blood screening in automated multiphasic health testing and services (AMHTS) is evaluated, and some problems with it are also discussed. A total of 54,735 subjects were screened for occult blood b...

Minamihara Y.; Mitsushima T.; Nagatani K.; Ueno F., 1992: Evaluation of fecal occult blood testing in colon cancer screening using total colonoscopy as the criterion standard. Gastroenterology 102(4 PART 2): A380

Yoshii Y.; Kobayashi S.; Matsuura A.; Kasugai T., 1984: Screening for colorectal cancer in clinical practice evaluation of fecal occult blood testing on 2 successive days. Fecal occult blood testing with guaiae impregnated filter paper slides (Shionogi slide B) was performed in 1003 subjects under a restricted diet on 3 successive days as screening for colerectal cancer at the outpatient clinic. Follow-up over a 3 y...

Schenck, A.P.; Klabunde, C.N.; Warren, J.L.; Peacock, S.; Davis, W.W.; Hawley, S.T.; Pignone, M.; Ransohoff, D.F., 2008: Evaluation of claims, medical records, and self-report for measuring fecal occult blood testing among medicare enrollees in fee for service. Background: There is no agreement on the best data source for measuring colorectal cancer (CRC) screening. Medicare claims have been used to measure CRC testing but the validity of using claims to measure fecal occult blood tests (FOBT) has not b...

Rubeca, T.; Peruzzi, B.; Confortini, M.; Rapi, S., 2013: Overall evaluation of an immunological latex agglutination system for fecal occult blood testing in the colorectal cancer screening program of Florence. Several immunological fecal occult blood tests (FOBT) are currently available for colorectal cancer (CRC) screening. We compared the HM Jack (Jack) (Kiowa, Japan), with the OC-Hemodia (OC) (Eiken, Japan) in use in the Florence screening program. A...

Schellenberger, U.; Raabe, A.; Erler, K., 1987: Screening test for colorectal cancer. Practical experiences with fecal testing for occult blood. 2: Rate of a false-negative occult blood test. Zeitschrift für Arztliche Fortbildung 81(20): 1057-1059

Goulston K., 1969: Chemical testing of occult blood in feces hematest occultest and guaiac testing correlated with chromium 51 estimation of fecal blood loss. Medical Journal Of Australia: 1291-1293