EurekaMag.com logo
+ Translate

Evaluation of a new progestin sa 45249 in cattle


, : Evaluation of a new progestin sa 45249 in cattle. Theriogenology 9(6): 509-522

Daily oral administration of the progestin Sa 45.249 to 80 cycling heifers, at doses ranging from 6-14 mg/day and over varying treatment periods (from 8-16 days), resulted in all animals in complete estrus inhibition. Irrespective of the dose and the treatment period used, heat and ovulations.sbd.as judged by the corpora lutea, which became palpable on day 15 of this cycle.sbd.occurred between days 2-9 after cessation of treatment in 73 of 80 heifers (91%). Neither the daily dose nor the duration of treatment had any discernible effect on heat occurrence. This pattern was confirmed in a pilot field trial. From artificial insemination at the 1st and 2nd heat after treatment, 16 of 21 treated heifers (76%) and 45 of 55 cows (80%) were pregnant. There was no difference in cyclic plasma progesterone levels between heifers treated for 14 days with 10 mg Sa 45.249 and untreated controls, when treatment commenced either on day 5 or 14 of the cycle, with the exception of the delay in the post-ovulatory rise in the latter treatment.

(PDF same-day service: $19.90)

Accession: 005395420

DOI: 10.1016/0093-691x(78)90116-4

Submit PDF Full Text: Here


Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:
Close
Close

Related references

Malmgren L.; Karlberg K.; Goransson L., 1983: Synchronization of estrus in gilts with a progestin oxolven sa 45249. An orally active synthetic progestin (Oxolven) was given in capsules to sexually mature gilts once daily for 12-14 days. The daily dose per animal was 6 mg (= 3 capsules). In trial I, 14 pairs of full-sibs were housed in pens (4-6 animals/pen). Al...

Mayer, P.; Schuetze, E., 1977: A new progestin sa 45249 17 beta hydroxy 17 alpha propadienyl estra 4 9 dien 3 one for cycle control in pigs part 1 hormonal activities and dosage. Sa 45.249 [17.beta.-hydroxy-17.alpha.-propadienylestra-4,9-diene-3-one] was applied for 12 days to groups of 10 gilts each. A daily dose of 3, 6, 12 or 24 mg inhibited cyclic functions effectively; estrus was observed 4.5 .+-. 0.8, 4.8 .+-. 0.8, 5...

Mayer, P.; Schuetze, E., 1977: A new progestin sa 45249 17 beta hydroxy 17 alpha propadienyl estra 4 9 dien 3 one for cycle control in pigs part 4 analysis of hormonal blood levels. Gilts were treated with 6 mg Sa 45.249 [17.beta.-hydroxy-17.alpha.-propadienylestra-4,9-diene-3-one] per day for 12-14 days, starting at various stages of the estrous cycle. Blood levels of LH [luteinizing hormone], estradiol-17.beta. and progeste...

Zerobin, K.; Schuetze, E.; Mayer, P., 1977: A new progestin sa 45249 17 beta hydroxy 17 alpha propadienyl estra 4 9 dien 3 one for cycle control in pigs part 3 confirmation of effectiveness in field trials. A novel progestin, Sa 45.249 [17.beta.-hydroxy-17.alpha.-propadienylestra-4,9-diene-3-one], was tested for its estrous cycle synchronization effects in field trials in more than 300 animals. Gilts treated orally with 6 mg Sa 45.249/day (as a top d...

Schuetze, E.; Mayer, P., 1977: A new progestin sa 45249 17 beta hydroxy 17 alpha propadienyl estra 4 9 dien 3 one for cycle control in pigs part 2 duration of treatment and effectiveness as an estrous cycle synchronizer. Cycling gilts were treated orally with 6 mg Sa 45.249 [17.beta.-hydroxy-17.alpha.-propadienylestra-4,9-diene-3-one] per day for 12, 15 or 18 days; heat occurred within 7.6 .+-. 2.3, 6.5 .+-. 1.9 and 6.3 .+-. 1.0 days after cessation of treatment,...

Johnson, K.R.; Erb, R.E., 1962: Maintenance of pregnancy in ovariectomized cattle with progestin compounds and their effect on progestin levels in the corpus luteum. Pregnancy was maintained following ovariectomy after 88 days with daily injections of 125 mg of Delalutin (17-alpha-hydroxyprogesterone-17-n-caproate) when the treatment was started at least 8 days before surgery. Daily injections of 50mg of repos...

Shelby D.R.; Cleavinger D.A., 1991: Evaluation of a combination of progestin and prostaglandin to synchronize estrus in cattle. Journal of Animal Science 69(SUPPL 1): 491

Jochle, W.S.hmalfeldt, B.H.rrmann, C.F.stner, S.J.rdan, E.S.hmid-Linder, A., 1976: Influences of a progestin on early phases of gestation in cattle: clinical experiences. 2. evaluation as an early pregnancy

Jochle, W.J.rdan, E.L.hoff, H.M.uer, M.M.ller, S.T.chunko, E., 1976: Influences of a progestin on early phases of gestation in cattle: clinical experiences. 1. evaluation of effects on early embryonic losses

Jochle, W.; Jordan, E.; Lohoff, H.; Mauer, M.; Muller, S.; Tschunko, E., 1976: Effects of a progestin on the early phases of pregnancy in cattle: clinical experiences. I. Evaluation of effects on early embryonic losses. In a double-blind field trial 177 repeat breeder cows or heifers were given 10 mg daily chlormadinone acetate (CAP) or a placebo pellet from 14 to 23 days after artificial insemination or service. On average, the animals had repeated cycling 3.71...