+ Site Statistics
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Evaluation of a new system ("Corvac") for separating serum from blood for routine laboratory procedures

, : Evaluation of a new system ("Corvac") for separating serum from blood for routine laboratory procedures. Clinical Chemistry 22(7): 1012-1016

We evaluated the suitability of a new system ("Corvac," Corning) for rapid, complete separation of cell-free serum from whole blood. Twenty-one different clinical chemical procedures were performed on about 1150 paired blood samples, several by more than one method, to afford a more comprehensive evaluation. The tube of clotted blood collected in the conventional manner ("Vacutainer") underwent a double centrifugation and served as the control sample, while its paired specimen collected in the new system was processed by a single centrifugation. We evaluated significant differences between the means of the paired samples, the standard deviations of the differences between the means, and the bias of the means for the values of each constituent for each collection method. For several tests we observed differences that were statistically but not clinically significant. Only in the case of lactate dehydrogenase were large differences consistently demonstrated.

Accession: 005395443

PMID: 1277497

Submit PDF Full Text: Here

Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:

Related references

Spencer, W.; Nelson, G.H.; Konicke, K.A., 1977: Use of "Corvac" system in serum iron determination. Clinical Chemistry 23(2 Pt. 1): 305-305

Janetzko, K.; Lin, L.; Eichler, H.; Mayaudon, V.; Flament, J.; Klüter, H., 2004: Implementation of the INTERCEPT Blood System for Platelets into routine blood bank manufacturing procedures: evaluation of apheresis platelets. Background and Objectives The INTERCEPT Blood System for Platelets utilizes amotosalen-HCl (S-59) in combination with ultraviolet A (UVA) light to inactivate viruses, bacteria, protozoa and leucocytes that may contaminate platelet concentrates (PC...

Hermsen, D.; Niederau, C.M.; Reinauer, H., 1999: Evaluation of the Paragon CZE 2000 capillary zone electrophoresis system for serum protein electrophoresis in routine clinical laboratory. Clinical Chemistry 45(6 PART 2): A50, June

Deback, C.; Géli, J.; Aït-Arkoub, Zïna.; Angleraud, F.; Gautheret-Dejean, Aès.; Agut, H.; Boutolleau, D., 2009: Use of the Roche LightCycler 480 system in a routine laboratory setting for molecular diagnosis of opportunistic viral infections: Evaluation on whole blood specimens and proficiency panels. The Roche LightCycler® 480 (LC480) system was evaluated for quantitative molecular diagnosis of opportunistic viral infections caused by human cytomegalovirus (HCMV), Epstein–Barr virus (EBV), human herpesvirus 6 (HHV-6) and BK virus (BK...

Cassagne, C.; Cella, A-Laure.; Suchon, P.; Normand, A-Cecile.; Ranque, S.; Piarroux, R., 2015: Evaluation of four pretreatment procedures for MALDI-TOF MS yeast identification in the routine clinical laboratory. MALDI-TOF MS-based yeast identification requires a pretreatment step for which four are described in the literature, i.e., direct smear, fast formic acid and two complete formic acid/acetonitrile extractions. In this study we compared the impact o...

Lindeman J.; Von Gise H.; Smid L.; Meijer C.J.L.M., 1982: Evaluation of the automation of immuno enzymatic procedures in a routine histo cyto pathological laboratory. Experience in the use of an automated staining machine over 18 mo. for lengthy histological and immunohistochemical stains in a routine pathology laboratory is described. The apparatus yields an important saving in time for technicians and can mai...

Mathies, J.C., 1974: Evaluation of a new device for rapidly separating serum or plasma from blood. The Sure-Sep serum-plasma separator (General Diagnostics, Morris Plains, NJ 07950) was evaluated. The apparatus consists of a funnel-shaped, polyethylene unit containing a thixotropic mixture, 1.026, of dimethylpolysiloxane and silica, whic...

Peabody, H.D.; Sundberg, R.H., 1950: Detection of pulmonary tuberculosis; comparative value of routine radiologic examinations and routine laboratory procedures. The abnormalities disclosed by the usual laboratory diagnostic procedures (blood cell count and hemoglobin determination, sedimentation rate determination, urinalysis, and serologic test for syphilis) are compared with the number revealed by stere...

Van Hoof, V.; Cluckers, H.; Verhaegen, V.; Truyens, M.; Rombouts, P.; D.G.oote, S.; Hek, J.; Molenaer, J.; Jones, E.; Schumacher, T.; Muller, E., 2001: Automation of internal quality control procedures in a routine clinical laboratory by implementation of an on-line QC program that interacts with the lab information system. Clinical Chemistry & Laboratory Medicine 39(Special Supplement): S137

O'brien, D.; Ibbott, F.; Pinfield, A., 1961: Critical evaluation of the new ultramicro system for routine clinical chemistry procedures. A comparison of the accuracy and reproducibility of the technics comprising the Beckman/Spinco Ultra-micro Analytical System showed that these were neither more accurate nor more time saving than conventional micro methods. The system, however, pr...