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Evaluation of a peptide formula milk in the management of infants with multiple git intolerance


, : Evaluation of a peptide formula milk in the management of infants with multiple git intolerance. Clinical Nutrition (Edinburgh) 7(3): 183-190

The use of an enteral peptide feed based on hydrolysed whey protein (Pepti Junior, Cow and Gate/Nutricia Ltd) was evaluated in 17 patients with complex GIT intolerances. Nine post surgical neonates were weaned onto the feed either following a period of parenteral nutrition [8] or after demonstrating intolerance of both breast milk and a lactose-free soy based formula. Eight infants admitted to a gastroenterology ward with multiple protein intolerances were also studied. Patients were fed to their nutritional requirements with the milk containing/100 ml; 67 kcal (280 kJ), 2.0 g protein, 3.7 g fat (50% MCT, 50% vegetable oil) and 6.7 g carbohydrate (98% maltodextrins). Patients were maintained on the feed for 7-45 weeks (mean 21 weeks). Full nutritional support was possible with the new formula in all but 2 children who had jejunostomies; in these patients > 50% of nutritional requirements were supplied by the enteral feed. All patients gained weight (mean 0.16Kg/week (SD 0.09)). With the exception of subclinical deficiency, no abnormalities of haematological, biochemical or vitamin states were observed. Post prandial plasma amino-acid concentrations were within acceptable limits and similar to those reported on standard whey based infant formulae. The feed appeared well tolerated in infants with GIT intolerances with no major complications in long term usage.

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Accession: 005395486

DOI: 10.1016/0261-5614(88)90023-4

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