EurekaMag.com logo
+ Translate

Evaluation of a rapid radiometric method for drug susceptibility testing of mycobacterium tuberculosis


, : Evaluation of a rapid radiometric method for drug susceptibility testing of mycobacterium tuberculosis. Journal of Clinical Microbiology 13(5): 908-912

A total of 106 isolates of M. tuberculosis were tested for drug susceptibility by the conventional 7H11 plate method and by a new rapid radiometric method using special 7H12 liquid medium with 14C-labeled substrate. Results obtained by the 2 methods were compared for rapidity, sensitivity and specificity of the new test method. There was 98% overall agreement between the results obtained by the 2 methods. Of a total of 424 drug tests, only 8 drug results did not agree, mostly in the case of streptomycin. This new procedure was rapid, with 87% of the test results reportable within 4 days and 98% reportable within 5 days as compared to the usual 3 wk required with the conventional indirect susceptibility test method. The rapid radiometric method seems to have the potential for routine laboratory use and merits further investigations.

(PDF 0-2 workdays service)

Order PDF Full Text

Close
Close

Click here to order any other PDF Full Text


Accession: 005395612

PMID: 6787076

Submit PDF Full Text: Here


Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:
Close
Close

Other references

Sambon, L. W., 1926: Observations and Researches on the Epidemiology of Cancer. Journal of Tropical Medicine London, 2916: 233-287

BROSS.W.; DADLEZ.Z., 1963: Dr. Zygmunt Dadlez. Polski Przeglad Chirurgiczny 35: 1319-1320

Narayan, O.; Sheffer, D.; Clements, J.E.; Tennekoon, G., 1985: Restricted replication of lentiviruses. Visna viruses induce a unique interferon during interaction between lymphocytes and infected macrophages. Lentivirus infections are characterized by a persistent, restricted type of virus replication in tissues. Using sheep and goat lentiviruses, whose target cells in vivo are macrophages, we explored virus-host cell interactions to determine whether...

LANE, D., 1963: The Role Of Surgery In The Treatment Of Ulcerative Colitis. Medical Journal of Australia 2: 527-532

Chomicz, L.; Walski, M., 1991: Ultrastructure of oncospheral envelopes of Diorchis elisae (Skrjabin, 1914) Spassky et Frese, 1961 (Cestoda, Hymenolepididae). Both of the primary cytoplasmic oncospheral envelopes (the outer and the inner) in D. elisae were similar to those in other viviparous cestodes. Their secondary components however, were distributed in a different manner. This was particularly clea...

Ohmomo A.; Ohishi M., 1987: Incidence of chlamydia trachomatis detected in the conjunctival sacs of neonates. Recently, many studies have drawn attention to Chlamydial ophthalmia neonatorum in relation to sexually transmitted diseases (STD). We have tested specimens from conjunctival sacs of normal neonates for Chlamydia trachomatis antigen and report the...

Jarrosay Speck, C.M.; Serrano Durán, C.; Rodríguez Blanco, E.; de Castro Morgado, M.I., 1999: Evaluation of the introductory course for nursing licensure. Faculty of Medical Sciences, February-June 1996. A cross sectional study of 20 nursing baccalaureates, 14 heads of department, 4 methodologists and 2 professors from the faculties of medical sciences of the country was conducted with the objective of assessing the efficiency of the introductory...

Hui, L.; Cheng, Z.; Feng, L., 2014: Identification and function analysis of pseudogenes. Pseudogenes, which have long been described as "fossils", play a very important role in eukaryotic genomes. Recently, studies on the so called "junk gene" have attracted more attention. Far from being silent, pseudogenes partic...

Nates-Parra, G.; Palacios, E.; Parra-H.A., 2009: Effect of landscape change on the structure of the sting-less bee community (Hymenoptera: Apidae) in Meta, Colombia. Stingless bees represent one of the most diversified components of the natural Apoidea fauna of pollinators in the tropics. They use diverse kinds of substrates and inhabit varied habitats. Some species are typical for some natural either artifici...

Strichartz, G.R.; Chiu, S.Y.; Ritchie, J.M., 1978: The effect of delta9-tetrahydrocannabinol on the activation of sodium conductance in node of Ranvier. Journal of Pharmacology and Experimental Therapeutics 207(3): 801-809