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Evaluation of a sepsis screen in the diagnosis of neonatal sepsis

Indian Pediatrics 24(1): 39-43
Evaluation of a sepsis screen in the diagnosis of neonatal sepsis
One hundred babies were prospectively studied to evaluate a sepsis screening consisting of micro ESR, gastric aspirate for polymorphs, absolute neutrophil count (ANC), band-neutrophil count ratio and CRP to show the relative efficacy of these tests. The sensitivity and specificity of these tests was determined. CRP was found to be the most sensitive (80%) and specific (91%) test. The combination of any two or more positive tests was found sensitive in 86% of cases and specific in 89.6%. Even if CRP was excluded from the sepsis screen the sensitivity of two or more positive tests in diagnosing infection was 83% and can be recommended as a satisfactory screening procedure where CRP is not available.

Accession: 005395690

PMID: 3666926

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