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Evaluation of agents to reduce microbial growth on dental prostheses of myelo suppressed cancer patients

, : Evaluation of agents to reduce microbial growth on dental prostheses of myelo suppressed cancer patients. Clinical Preventive Dentistry 6(2): 9-12

The antimicrobial activity of 14 commerically available denture cleaners or oral antiseptics was tested against representative strains of organisms known to be pathogenic in myelosuppressed cancer patients and recovered frequently from dentures or denture-soaking cups of these patients. The mimimum inhibitory concentration level of each agent, as determined by standard tube dilution tests, against Pseudomonas aeruginosa, Klebsiella pneumoniae, Enterobacter cloacae, Escherichia coli, Staphylococcus aureus, Candida albicans and Torulopsis glabrata was measured. Six agents, Kleenite, Efferdent, Polident, Listerine, Chloraseptic and 1% Chlorhexidine glucoante, inhibited all test organisms at a dilution of 1:4. The use of these or other effective disinfecting agents for dentures might prevent contamination of the oral cavity by denture-borne microflora which has the potential to colonize and infect cancer patients.

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Accession: 005395986

PMID: 6331948

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