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Evaluation of bronchial hyperresponsiveness in asthmatic children measuring by methacholine inhalation challenge



Evaluation of bronchial hyperresponsiveness in asthmatic children measuring by methacholine inhalation challenge



Arerugi 34(9): 837-842



Methacholine inhalation tests were carried out using Astograph on 68 asthmatic children and 20 diseased children without respiratory disorders. The following results were obtained. 1) In non-asthmatic children, Dmin of six to nine year-old subjects were lower than that of ten to fifteen year-old subjects. There was no difference in it between the two groups. 2) In six to nine year-old and ten to fifteen year-old asthmatic children, Dmin of patients with moderate and severe asthmatic symptoms was lower than that of patients with mild symptoms. In six to nine year-old children, Dmin of non-asthmatic children was not higher than that of children with mild asthmatic symptoms, but was higher than that of children with moderate or severe asthmatic symptoms. 3) There was no significant difference in St between six to nine year-old non-asthmatic children and asthmatic children of the same age. But St of ten to fifteen year-old asthmatic children was higher than that of non-asthmatic children of the same age. 4) In evaluating bronchial hyperresponsiveness in asthmatic children, age seems to be a very important factor.

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Accession: 005396806

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PMID: 3909996


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