Evaluation of Mic Roc Rystal Line Cellulose Prepared from Absorbent Cotton as a Direct Compression Carrier
Singla, A.K.; Sakhuja, A.; Malik, A.
Drug Development and Industrial Pharmacy 14(8): 1131-1136
ISSN/ISBN: 0363-9045 Accession: 005399786
A study has been carried out to examine the feasibility of the use of microcrystalline cellulose (MCC-A) prepared from the absorbent cotton as a direct compression carrier. Tablets made with MCC-A were of equally good quality. The release of test drug diazepam from the tablets was faster than from the tablets made with two MCC commercial grades (MCC-B and MCC-C). The compressional forces - disintegration profile was also comparable.