Section 6
Chapter 5,400

Evaluation of Mic Roc Rystal Line Cellulose Prepared from Absorbent Cotton as a Direct Compression Carrier

Singla, A.K.; Sakhuja, A.; Malik, A.

Drug Development and Industrial Pharmacy 14(8): 1131-1136


ISSN/ISBN: 0363-9045
Accession: 005399786

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A study has been carried out to examine the feasibility of the use of microcrystalline cellulose (MCC-A) prepared from the absorbent cotton as a direct compression carrier. Tablets made with MCC-A were of equally good quality. The release of test drug diazepam from the tablets was faster than from the tablets made with two MCC commercial grades (MCC-B and MCC-C). The compressional forces - disintegration profile was also comparable.

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