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Evaluation of renal magnesium excretion in chronic renal failure



Evaluation of renal magnesium excretion in chronic renal failure



Polskie Archiwum Medycyny Wewnetrznej 54(2): 163-168



In 42 patients with chronic renal failure during chronic glomerulonephritis and pyelonephritis the 24-h excretion of Mg2+ decreased with progressing renal failure and was independent of the total and ultrafiltrable Mg2+ concentration in the plasma. At the same time the fractional excretion of this ion increased progressively probably as a result of increased osmotic load acting on individual nephrons and/or the action of the natriuretic factor. The high correlation between fractional excretion of Mg2+ and Na+ and Mg2+ and Ca2+ may suggest an interrelationship between the transport mechanisms of these ions in the nephron.

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Accession: 005401115

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