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Evidence of a thromboxane a 2 calcium complex a conformational approach

, : Evidence of a thromboxane a 2 calcium complex a conformational approach. Research Communications in Chemical Pathology & Pharmacology 46(2): 175-186

Thromboxane A2 has been proposed as an ionophore capable to transport Ca from the platelet dense tubular system to the cytoplasm to activate the contractile proteins. However, the half-life (30 s) of this compound limits considerably the experimental approach. The conformational analysis is proposed here as a possible way to identify such transient conformations. There is evidence of the existence of 2 Ca2+-thromboxane A2 isomeric complexes: one structure responsible for the complexation-decomplexation process at the interface and one lipophilic structure able to cross the lipid membrane.

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Dorogi P.L., 1984: Kinetics and mechanism of calcium binding to arsenazo iii and antipyrylazo iii. Equilibrium and temperature-jump spectrophotometric measurements were carried out on arsenazo III (Ar) and antipyrylazo III (Ap) in order to establish the kinetic reaction schemes for complexing of these dyes with Ca2+. The reaction media containe...

Knusel B.; Michel P.P.; Schwaber J.S.; Hefti F., 1990: Selective and nonselective stimulation of central cholinergic and dopaminergic development in vitro by nerve growth factor basic fibroblast growth factor epidermal growth factor insulin and the insulin like growth factors i and ii. To study the selectivity of neurotropic actions in the brain, we analyzed the actions of several known growth factors on septal cholinergic, pontine cholinergic, and mesencephalic dopaminergic neurons in culture. Similar to nerve growth factor (NG...

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Spada G.; Sabadini R.; Boschi E., 1995: On the long-term rotational dynamics of the Earth and terrestrial planets. International Union of Geodesy and Geophysics, General Assembly 21, Week B: 34

Boyd, William C., 1943: Fundamentals of immunology. This thoroughly modern volume upon a subject which is no older than the Pfeiffer phenomenon is a valuable reference work for the teacher and the investigator, it is likewise a dependable text for the medical student and especially for persons prep...

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Dr. Y. D. Heilbronn; Dr. F. Tovi; Dr. M. Hirsch; Dr. J. Ronen, 1984: Transverse cervical myelopathy an unusual complication of retropharyngeal abscess. Head & Neck 6(6): 1051-1053

Portoles M.T.; Pagani R.; Diaz Laviada I.; Municio A.M., 1987: Effect of escherichia coli lipopolysaccharide on the microviscosity of liver plasma membranes and hepatocyte suspensions and monolayers. The fluorescence probe 1,6-diphenylhexa-1,3,5-triene (DPH) was used for monitoring structural perturbations induced by lipopolysaccharide (LPS) of Escherichia coli (0111:B4) in plasma membranes of rat liver. Changes in microviscosity were observed...

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