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Evidence of adrenergic and cholinergic receptors in teleost melanophores


Comparative Biochemistry & Physiology C Comparative Pharmacology 70(2): 293-296
Evidence of adrenergic and cholinergic receptors in teleost melanophores
Melanophores of Bathygobius soporator aggregated in the presence of highly concentrated catecholamines, antagonized by phentolamine. In lower doses, the catecholamines promoted a melanosome dispersion, blocked by propranolol. Isoproterenol was unable to induce pigment dispersion. Melanosome dispersion was obtained with cholinester and alkaloid treatments, inhibited by atropine and d-tubocurarine. The presence of 2 different types of receptors are assumed; adrenoceptors, uncharacterized in respect to their .alpha.- or .beta.-nature, and cholinoceptors, undifferentiated in relation to muscarinic or nicotinic nature.

Accession: 005411200

PMID: 6118232

DOI: 10.1016/0306-4492(81)90068-X

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