EurekaMag.com logo
+ Site Statistics
References:
52,725,316
Abstracts:
28,411,598
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Evidence of anti hla a cyto toxins with only bone marrow derived lymphocytes


Tissue Antigens 13(1): 75-76
Evidence of anti hla a cyto toxins with only bone marrow derived lymphocytes
Sera [human] containing cytotoxins against antigens of the HLA[histocompatibility antigen]-A locus in some cases yielded positive reactions only with B [bone marrow derived] lymphocytes of a certain donor, but not with his T [thymus derived] lymphocytes. Such results may create a false idea as to the presence of a pool of antibodies against antigens of the HLA-A (B) locus and against specific antigens of B lymphocytes in the serum. Positivity with B cells vs. negativity with total peripheral lymphocytes is an insufficient criterion for defining B cell antibodies. For differentiation of both antibody types the method based on blocking HLA-A, -B, -C receptors by anti-B2 -microglobulins, as described by Bernoco et al. (1976), seems the most suitable.


Accession: 005411253



Related references

Hetero anti sera prepared against bone marrow derived lymphocytes at different stages of differentiation part 2 functional analysis of cyto toxicity to different bone marrow derived cell populations. Immunology 32(5): 717-729, 1977

Anti bone marrow derived and thymus derived cell activity of anti serum to spleen cells of athymic nu nu mice evidence for surface antigenic differences between functionally distinct subclasses of thymus derived and bone marrow derived lymphocytes. Archivum Immunologiae et Therapiae Experimentalis 24(5): 671-688, 1976

Cyto toxic anti serum against bone marrow derived lymphocytes prepared by immunization with bone marrow cells. Byulleten' Eksperimental'noi Biologii i Meditsiny 83(2): 194-196, 1977

Suppressor thymus derived lymphocytes and auto anti bone marrow derived cell cyto toxic thymus derived lymphocytes in a case of acquired hypo gamma globulinemia. Scandinavian Journal of Haematology 24(1): 80-86, 1980

Ultrastructural and serological studies on the resistance of activated bone marrow derived cells to the cyto toxic effects of anti immuno globulin serum patch and cap formation of surface immuno globulin on mitotic bone marrow derived lymphocytes. Clinical & Experimental Immunology 20(1): 161-178, 1975

Complement dependent cyto lysis of human bone marrow derived lymphocytes with anti light chain anti sera. European Journal of Immunology 4(5): 332-337, 1974

Pre bone marrow derived cells bone marrow persistence in anti mu suppressed mice conversion to bone marrow derived lymphocytes and recovery after destruction by cyclo phosphamide. Journal of Immunology 120(5): 1526-1531, 1978

Maturation of bone marrow derived lymphocytes in the rat part 1 migration pattern tissue distribution and turnover rate of unprimed and primed bone marrow derived lymphocytes involved in the adoptive anti di nitro phenyl response. Journal of Experimental Medicine 138(6): 1331-1344, 1973

Murine anti h 2 k sera exhibit a strong cyto toxic effect on human bone marrow derived lymphocytes. Immunogenetics 9(6): 591-596, 1979

Resistance of mitotic bone marrow derived lymphocytes to cyto toxic effects of anti immuno globulin serum. Nature (london)464): 342-344, 1974