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Evidence of digoxin metabolism by the kidney

, : Evidence of digoxin metabolism by the kidney. Canadian Journal of Physiology & Pharmacology 65(12): 2500-2503

By performing single pass experiments in the dog, we could identify by thin layer chromatography a digoxin metabolite produced by the kidney. In vitro studies verify that this new species is produced by the brush border membrane of the renal tubular cell.

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Accession: 005411356

PMID: 3449207

DOI: 10.1139/y87-398

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