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Evidence of genetic factors in hidradenitis suppurativa


British Journal of Dermatology 113(1): 1-8
Evidence of genetic factors in hidradenitis suppurativa
Probands [26] suffering from hidradenitis suppurativa were identified. Investigation of their families eventually confirmed a total of 62 affected individuals from 23 families. In 11 families there was evidence in favor of single gene or Mendelian inheritance; in another 3 there was familial occurrence; in 9 families there was a negative family history at the time of enquiry. The disease appears to be commoner than reports suggest and it is probable that there is an underestimation of affected individuals in the community. Problems of identification including variable age of onset and psycho-social factors were found and may be responsible for false-negative family histories.

Accession: 005411431

PMID: 4015966

DOI: 10.1111/j.1365-2133.1985.tb02037.x

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