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Evidence of glomerular basement membrane antigens excretion in normal rat urine


, : Evidence of glomerular basement membrane antigens excretion in normal rat urine. Comptes Rendus des Seances de la Societe de Biologie et de ses Filiales 171(2): 355-360

Rabbit antibodies were against rat GBM, with GBM prepared from isolated glomeruli issued from rat renal cortex. It was shown using immunodiffusion that there was excretion of basement membrane-like fragments into normal rat urine. The origin and the nature of this pattern as well as the significance of the presence of antigens in mammalian urine were discussed.

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Related references

Lerner, R.A.; McPhaul, J.J.; Dixon, F.J., 1968: Soluble glomerular basement membrane antigens in normal urine--possible autoimmunogens in man. Annals of Internal Medicine 68(1): 249-250

Cambar J.; Piquet Y.; Montoriol J.; Mesnier Y., 1978: Evidence of urinary glomerular basement membrane antigens excretion in 3 rodents rat mouse and guinea pig. Experientia (Basel) 34(6): 747-748

Cambar, J.; Piquet, Y.; Montoriol, J.; Mesnier, Y., 1978: Evidence of urinary glomerular basement membrane (GBM) antigens excretion in 3 rodents (rat, mouse, and guinea-pig). Immunodiffusion technique, with rabbits antibodies against rat glomerular basement membrane (GBM), permits to evidence the presence of GBM antigens into normal urines of 3 rodents (rat, mouse, and guinea-pig). These results confirm the earlier wor...

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