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Evidence of homology between the beta chain of human hapto globin and the chymotrypsin family of serine proteases






Biochemical Genetics 11(4): 279-293

Evidence of homology between the beta chain of human hapto globin and the chymotrypsin family of serine proteases



Accession: 005411471

PMID: 4210109



Related references

Kurosky A.; Barnett D.R.; Rasco M.A.; Lee T H.; Kim H.H.; Bowman B.H., 1973: Homology of the hapto globin beta chain with the serine proteases. American Journal of Human Genetics 25(6): 43A

Hamaguchi H., 1967: Control of hapto globin metabolism physicochemical human hapto globin 1 1 type/ properties of the hemo globin hapto globin complex of. Proceedings of the Japan Academy 43(6): 562-565

Kazim A.L.; Atassi M.Z., 1980: Hemo globin binding with hapto globin unequivocal demonstration that the beta chains of human hemo globin bind to hapto globin. Haptoglobin binding to [adult human] Hb and its isolated .alpha.- and .beta.-chains was studied by use of a highly sensitive solid-phase radiometric assay. Adsorbents of Hb bound 125I-labelled haptoglobin more efficiently than did adsorbents of th...

Kazim A.L.; Atassi M.Z., 1981: Hemo globin binding with hapto globin localization of the hapto globin binding site on the alpha chain of human hemo globin. A synthetic approach was employed to identify the haptoglobin-binding site on the .alpha.-chain of human Hb. This approach consists of the synthesis of a series of consecutive overlapping peptides that, together, systematically represent the entir...

Hay R.E.; Kurosky A., 1976: Cyanogen bromide fragments of human hapto globin beta chain. Federation Proceedings 35(7): 340

Lee T H.; Lee M J.; Ghim G J.; Barnett D.R.; Bowman B.H., 1982: Characterization of a ninhydrin negative peptide from human hapto globin beta chain. A ninhydrin-negative tridecapeptide was isolated from human haptoglobin .beta.-chain. The terminal amino group of the peptide was blocked and did not react with Edman reagent. The carboxyl-terminal sequence was determined by carboxypeptidase diges...

Hamaguchi H., 1966: Control of hapto globin metabolism ii purification of hapto globin hemo globin hapto globin subunits and hemo globin hapto globin complexes. Proceedings Of The Japan Academy: 1104-1109

Hamaguchi H., 1968: Control of hapto globin metabolism part 5 hemo globin binding capacity of 3 common phenotypes of human hapto globin molecules. Proceedings of the Japan Academy 44(7): 733-738

Constans J.; Viau M.; Gouaillard C.; Clerc A., 1981: Hapto globin polymorphism among saharian and west african groups hapto globin phenotype determination by radio immuno electrophoresis on hapto globin o samples. The haptoglobin (Hp) polymorphism is investigated in 11 African groups living in an area from the Algerian Sahara to Central Africa. More than 4000 samples were examined. In the Saharian samples, the Hp1 gene frequency is higher than in any other...

Schmidt, A.E.; Sun, M-fu.; Ogawa, T.; Bajaj, S.Paul.; Gailani, D., 2008: Functional role of residue 193 (chymotrypsin numbering) in serine proteases: influence of side chain length and beta-branching on the catalytic activity of blood coagulation factor XIa. In serine proteases, Gly(193) (chymotrypsin numbering) is conserved with rare exception. Mutants of blood coagulation proteases have been reported with Glu, Ala, Arg or Val substitutions for Gly(193). To further understand the role of Gly193 in pr...