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Evidence of myotonic origin of type 2b muscle fiber deficiency in myotonia and paramyotonia congenita


, : Evidence of myotonic origin of type 2b muscle fiber deficiency in myotonia and paramyotonia congenita. Journal of the Neurological Sciences 76(2-3): 357-359

Available experimental and clinical evidence strongly suggests that deficiency in type 2B muscle fibers in generalized myotonia and paramyotonia congenita will develop consequent to lasting myotonic activity as its adequate stimulus. Type 2B fibre deficiency need not be regarded as the product of a hypothetical genetic factor.

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