+ Site Statistics
+ Resolve Accession
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
Submit PDF Full TextSubmit PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Evidence of noncholinergic excitatory nervous transmission in chick ileum

, : Evidence of noncholinergic excitatory nervous transmission in chick ileum. Life Sciences 22(12): 1049-1058

Whether ATP or some other purine nucleotide plays a neurotransmitter role in the chick gut was studied. ATP, ADP and AMP produced a dose-dependent contraction of the isolated ileum. The effective concentration of 50% (EC50) of ATP was 20 times less than that of ADP and much less than that of AMP. ATP-induced contractions were completely resistant to blockade either by atropine or promethazine and were partially resistant to blockade by methysergide. Quinine blocked the effect of ATP, carbachol, 5-HT [serotonin] and histamine while caffeine blocked the effect of ATP only. Electrical stimulation of Remak's nerve resulted in contraction of the ileum which resembled that produced by ATP. The electrically-induced contraction was not affected by atropine, promethazine and methysergide but was blocked by either quinine or caffeine. ATP or a related compound may be acting as a chemical transmitter in Remak's nerve supplying the sympathetic innervation to the ileum of the chick.

Order PDF Full Text


Click here to order any other PDF Full Text

Accession: 005411609

PMID: 205749

DOI: 10.1016/0024-3205(78)90274-6

Download PDF Full Text: Evidence of noncholinergic excitatory nervous transmission in chick ileum

Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:

Other references

Nikodijevic, O.; Jacobson, K., A.; Daly, J., W., 1993: Acute treatment of mice with high doses of caffeine: An animal model for choreiform movement. Injection of caffeine at a dose of 35 to 70 mg/kg causes choreiform (dance-like) movements in NIH Swiss mice in a dose-dependent manner. The effect is less pronounced in mice that had chronically ingested caffeine for 7 days. The A-2a selective ad...

Kosterman, R.; Hill, K.G.; Lee, J.Olivia.; Meacham, M.C.; Abbott, R.D.; Catalano, R.F.; Hawkins, J.David., 2016: Young adult social development as a mediator of alcohol use disorder symptoms from age 21 to 30. Little research has examined social development in the young adult years relative to childhood and adolescence. This study tested the hypothesized pathways of the social development model (SDM) in young adulthood for predicting symptoms of alcohol...

Srivatsan, E.S.; Padayatty, J.D., 1976: Rice embryo cell-free system for the synthesis of T4 phage proteins. Indian Journal of Biochemistry & Biophysics 13(3): 284-286

Roy, J.; Denovan-Wright, E.M.; Linsdell, P.; Cowley, E.A., 2006: Exposure to sodium butyrate leads to functional downregulation of calcium-activated potassium channels in human airway epithelial cells. Cystic fibrosis (CF) is caused by genetic mutations that lead to dysfunction of the cystic fibrosis transmembrane conductance regulator (CFTR) Cl- channel. The most common mutation, Delta F508, causes inefficient trafficking of mutant CFTR protein...

Walsh, P.C.; Lepor, H., 1987: The role of radical prostatectomy in the management of prostatic cancer. The indications for radical prostatectomy must reflect the following: an understanding of the natural history of the disease, the projected life span of the patient, the stage of the disease, and the relative morbidity and efficacy of alternative...

Botz, F.; Sieger, A., 1984: Meckel's diverticulum as the cause of intestinal obstruction in the horse. Tierarztliche Praxis 12(2): 217-218

Jeddi, R.S.loua.; Pickford, M..; Tassy, P..; Coppens, Y.., 1991: Discovery of mammals in the Tertiary of central Tunisia; biostratigraphic and paleogeographic implications. Comptes Rendus de l'Academie des Sciences Serie II Mecanique-Physique-Chimie Sciences de l'Univers Sciences de la Terre. 28 Fevrier; 3125: 543-548

Etkin, L.D., 1977: Preferential expression of the maternal allele for alcohol dehydrogenase (ADH) in the amphibian hybrid Ambystoma mexicanum (axolotl) x Ambystoma texanum. Developmental Biology 60(1): 93-100

Walcott, M.M.; Jolly, P.E.; Ehiri, J.E.; Funkhouser, E.; Kempf, M.C.; Hickman, D.; Aung, M.; Zhang, K., 2014: Factors associated with the acceptability of male circumcision among men in Jamaica. To determine the prevalence of male circumcision (MC) among men in the western region of Jamaica, and to identify factors associated with acceptability of MC for self, infants (<1 year) and older sons (1-17 years). A cross-sectional, interv...

Teichman, Y., 1974: Predisposition for anxiety and affiliation. Journal of Personality and Social Psychology 29(3): 405-410