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Evidence of persistent viral infection in meniere's disease

, : Evidence of persistent viral infection in meniere's disease. Archives of Otolaryngology Head and Neck Surgery 113(4): 397-400

Aspects of humoral and cell-mediated immunity that might characterize the continuation of symptoms in 25 patients with chronic Meniere's disease were examined. We found significant elevations of both humoral and cellular immune responses to viral antigens of herpes simplex I, varicella-zoster, rubella, and cytomegalovirus. Serum immunoglobulins were quantitatively abnormal in 24 of 25 patients, without a consistent pattern. These immune response may be linked to persistent viral infection in chronic Meniere's disease.

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Accession: 005411640

DOI: 10.1001/archotol.1987.01860040059017

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