+ Site Statistics
+ Resolve Accession
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
Submit PDF Full TextSubmit PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Evidence of place conditioning after chronic intrathecal morphine in rats

, : Evidence of place conditioning after chronic intrathecal morphine in rats. Pharmacology Biochemistry & Behavior 22(2): 271-278

The acute administration of systemic or intrathecal morphine produced an antinociceptive reaction on the tail flick test; only systemic morphine produced a sedative effect on motor activity. Rats receiving chronic intrathecal injections were hyperactive relative to saline injected control subjects. After a series of 4 injections, a place preference was induced by both routes of administration; rats who had previously received morphine either by s.c. or intrathecal injection spent significantly more time in the context in which the drug had been given, relative to rats who were comparably injected with saline. Apparently, chronic intrathecal morphine in rats may elicit a discriminable cue, either through direct pharmacological stimulation of supraspinal sites, or, indirectly, as a consequence of spinal opiate action.

Order PDF Full Text


Click here to order any other PDF Full Text

Accession: 005411652

PMID: 3838587

DOI: 10.1016/0091-3057(85)90390-9

Download PDF Full Text: Evidence of place conditioning after chronic intrathecal morphine in rats

Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:

Other references

Banerjee, A.; Bose, A., 1969: Specific gravity of cell types in differentiating central nervous system of chick. Experientia 25(5): 496-496

Anonymous, 1976: Diary products: situation and outlook. This report, one of a series of regular commodity reports, makes an overall appraisal of the dairy market situation and outlook in Australia. Factors influencing future domestic and internal developments are examined, as well as recent development...

Hajjarian, Z.; Nadkarni, S.K., 2015: Estimation of particle size variations for laser speckle rheology of materials. Laser speckle rheology (LSR) is an optical technique for assessing the viscoelastic properties of materials with several industrial, biological, and medical applications. In LSR, the viscoelastic modulus, G*(ω), of a material is quantified by ana...

Bibby, B., 1988: Reflections on a distinguished career: Dr. Basil Bibby: 1988 ADA Gold Medal Award winner. Journal of the American Dental Association 117(5): 571-575

Adams, S., 1987: Blueberries from field to muffin tin. Agricultural research US Department of Agriculture Agricultural Research Servicey 35(6): 10-13

Meyer, O.; Descamps, B., 1979: Detection of soluble immune complexes by the technique of ADCC inhibition in human diseases. Soluble immune complexes were detected using inhibition of antibody-dependent cell-mediated cytotoxicity (ADCC) in sera of patients with various diseases. Results were positive in 32/41 patients with rheumatoid arthritis (78%), in 27/38 systemic l...

Ryan, J.M.; Smith, P.J.S.; Tytell, M., 1994: H-2O-2 induced perturbation of neuronal physiology and morphology. In Vitro Cellular & Developmental Biology Animal 30A(3 PART 2): 91

Lyng, H.; Rofstad, E.K., 1995: Treatment failure following sequential thermoradiotherapy of locally advanced breast carcinoma occurs primarily in poorly vascularized tumors. Sequential thermoradiotherapy was given to 24 patients with locally advanced breast carcinoma. The outcome of treatment was analyzed in relation to the thermal dose as well as clinical stage, tumor volume, vascular density and necrotic fraction pr...

Isaac, J.; Chen, Y.; Stockley, E.; Chad, J.; Wheal, H.V., 1994: Three-dimensional morphological reconstruction of CA1 pyramidal neurons in the epileptiform hippocampus. Society for Neuroscience Abstracts 20(1-2): 399

Brethes, J., 1913: Un nouveau genre et une nouvelle espece de Cynipide du Chili. Revista Chilena Santiago, 17 159-161