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Evidence of the existence of a factor that induces Fc receptors on bone marrow cells

, : Evidence of the existence of a factor that induces Fc receptors on bone marrow cells. Blood 59(4): 756-760

The existence of a molecule responsible for the induction of Fc receptor (FcR) on bone marrow cells (FcR inducer, FcRI) is demonstrated in conditioned media from the macrophage-like cell line WR19M.1 activated by bacterial lipopolysaccharides. The molecular weight obtained from molecular sieving chromatography in gel and density gradient sedimentation is found to be 18,500 daltons and 16,000 daltons, respectively, with an isoelectric pH of 7.4. The factor is found to be thermolabile and trypsin sensitive. The macrophage and granulocyte inducer (MGI), also known as colony-stimulating factor (CSF) or colony-stimulating activity (CSA), is identified from the same source and found to have a molecular weight and an isoelectric pH different from FcRI. The fractions that contained the MGI did not induce FcR on bone marrow cells, while the fractions rich in FcRI did not induce colony formation.

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Accession: 005411775

PMID: 7059677

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Boily J. F.; Fein J. B., 1996: Pb-benzenecarboxylate co-adsorption on alpha -corundum. Abstracts of Papers - American Chemical Society, National Meeting 211: GEOC 078

Repetski, J. E., 1981: An Ordovician occurrence of Utahphospha Muller Miller. The problematic phosphatic microfossil Utahphospha Mueller and Miller has been recovered from upper Lower Ordovician rocks of the El Paso Group in western Texas. This genus, and related forms, have been reported previously only from Cambrian strat...

Foissner, I.; Wasteneys, G. O., 2000: Microtubule disassembly enhances reversible cytochalasin-dependent disruption of actin bundles in characean internodes. Parallel bundles of actin filaments at the cortex-endoplasm interface provide tracks for myosin-generated cytoplasmic streaming in characean internodes. These bundles resist disassembly or structural modification when exposed to 10 muM cytochalasi...

Gray, M.; Charpentier, A.; Walsh, K.; Wu, P.; Bender, W., 1991: Mapping point mutations in the Drosophila rosy locus using denaturing gradient gel blots. Mutations within the rosy locus of Drosophila were mapped using blots of genomic DNA fragments separated on denaturing gradient gels. DNA sequence differences between otherwise identical small rosy DNA fragments were detected among the mutants as...

Bermudez, J. J.; Perez, M.; Pampin, M.; Torres, R., 1989: A comparison of laying hens of some new genotypes. The performance was compared of 480 hens of the L12, L63, L151, L152 and L13 White Leghorn strains, the last 4 of which may be sexed on the basis of feather length. For birds of the 5 strains, body weight at 15 wk of age averaged 1201.5, 1145.1, 1...

Rennie, Rj, 1984: Innovative agriculture through biotechnology. Agriculture and forestry bulletin Alberta University Faculty of Extension 7(1): 5-11

Fry, J. D., 1989: Evolutionary adaptation to host plants in a laboratory population of the phytophagous mite Tetranychus urticae Koch. For evolutionary expansion of host range to occur in a herbivore population, genetic variation in the ability to survive on and/or accept new hosts must be present. To determine whether a population of Tetranychus urticae contained such variation,...

Paterson, A. G.; Harwin, G. O.; Ehret, W. J.; Avis, W.; Twine, H. E., 1983: Artificial insemination versus natural breeding in a multi-breed beef herd under intensive management. 828 crossbred beef and dual-purpose cows were allocated to 3 herds which were (1) inseminated, (2) inseminated and naturally mated, or (3) naturally mated only. The CRs were 72.9, 88.2 and 94.3% resp. (P less than 0.01). For CR, the superiority of...

Barkoff, E., 1959: The fractionation of soil phosphates by means of an automatic apparatus containing ion exchangers.. By using suitable ion exchangers (Dowex 50, Dowex 50 + IRA-400) in the apparatus and an appropriate extradant (0.01 n KCl, 1/15 n KOH, 0.2 n H2SO4) for the soil sample, the soil P can be separated into three fractions representing: (1) P in equili...

Estevens C.A., 1989: Medical lasers in portugal panorama and proposals. Lasers in Medical Science (SUPPL): 239-242