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Evidence of vagal neuropathy in chronic alcoholics


, : Evidence of vagal neuropathy in chronic alcoholics. Lancet 2(8203): 1053-1057

Autonomic function was tested in healthy control subjects and 20 chronic alcoholic patients with varying degrees of alcohol-related peripheral and central neurological damage. The alcoholics were divided into 2 groups according to the severity of their symptoms and signs. The alcoholic subjects had no postural hypotension. Heart-rate responses to Valsalva's maneuver, deep breathing, change in posture, baroreceptor stimulation and atropine were lower in those alcoholics with a greater degree of peripheral and central nervous damage than in the less severely affected alcoholics and the controls. These results suggest that chronic vagal damage may be a feature of alcoholic polyneuropathy.

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Accession: 005411836

PMID: 6107680

DOI: 10.1016/S0140-6736(80)92275-8

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