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Evidence on the periodic mechanism in herpes simplex encephalitis


Electroencephalography & Clinical Neurophysiology 46(3): 345-350
Evidence on the periodic mechanism in herpes simplex encephalitis
A [human] case of herpes simplex encephalitis is described in which the EEG was recorded 5 times between the 5th day of illness and death on the 13th day. Repetitive discharges occurred at intervals of 3.5 or 2 s; at first they were larger and earlier on the right side, finally on the left; on day 11 they could be earlier on either side and sometimes ceased briefly on either side. They were associated with jerks. This periodicity cannot be explained by cortical isolation or a single pacemaker and hence favors a 3rd possibility, a more or less diffuse disturbance of the time constant of excitability at the cellular level.

Accession: 005411866

PMID: 85527

DOI: 10.1016/0013-4694(79)90208-6

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