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Evidence suggestive of diffuse brain damage following cardiac operations


, : Evidence suggestive of diffuse brain damage following cardiac operations. Lancet 1(8381): 816-820

In 37 patients regional cerebral blood flow (rCBF) was measured by single photon emission computerized tomography (SPECT) after inhalation of 133Xe before and within the 1st 10 days after open heart surgery for acquired or congenital heart disease. None of the patients had motor deficits postoperatively and no focal abnormalities were disclosed by the rCBF tomograms. rCBF was generally reduced and mean CBF fell from a normal value of 53.5 to 44.7 ml/100 g .cntdot. min (P < 0.001). Changes in rCBF occurred uniformly throughout the brain. The reduction in CBF correlated positively with increasing years (P < 0.05), duration of extracorporeal circulation (P < 0.05) and low mean arterial blood pressure during the bypass (P < 0.02). It was generally more pronounced after valve replacement than after coronary bypass (P < 0.16). In 11 patients investigated 1 yr after surgery CBF remained slightly reduced, 50.5 ml/100 g .cntdot. min (P < 0.05). No CBF reduction occurred in a control group of 15 patients who underwent carotid endarterectomy or extracranial-intracranial shunt operations. The findings are consistent with the suggestion that the extracorporeal circulation causes early postoperative CNS dysfunction.

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Accession: 005411917

PMID: 6143139

DOI: 10.1016/S0140-6736(84)92271-2

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Ando, M.; Miyazaki, E.; Bishai, W.R., 2000: Virulence attenuation in Staphylococcus aureus RN6390 by overexpression of an intact rsbU-sigB operon. Abstracts of the General Meeting of the American Society for Microbiology 100: 235

Cappelletti, G., 1967: Technology, production and chemical and nutritional characteristics of 'Marzolino' a typical cheese of Sienese hills. Marzolino cheese, produced on a small scale on farms in the Siena valley, is made from whole ewes' milk, which is filtered, left to stand overnight and then heated in a water bath on a wood fire. 100-130 g presame (a rennet obtained from card...

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