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Evidence that a decrease in opioid tone on proestrus changes the episodic pattern of luteinizing hormone lh secretion implications in the preovulatory lh hypersection


, : Evidence that a decrease in opioid tone on proestrus changes the episodic pattern of luteinizing hormone lh secretion implications in the preovulatory lh hypersection. Endocrinology 122(3): 1004-1013

We have studied the LH secretion pattern evoked by diminution in the opioid tone produced by iv naloxone (NAL) infusion beteen 1100-1400 h on proestrus, the LH secretion pattern occurring spontaneously between 1430-1730 h on proestrus and the LH secretion pattern produced by exogenous LHRH administered either as a 10 ng/pulse at 20-, 30-, or 60-min intervals or infused continuously at a rate fo 30 ng/h between 1200-1700 h in rats given pentobarbital at 1100 h on proestrus.

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