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Exogenous hyper thermia and hydro electric homeostasis






Revue Roumaine de Morphologie d'Embryologie et de Physiologie Physiologie 17(2): 85-90

Exogenous hyper thermia and hydro electric homeostasis

When a human is exposed for 1 h to an environment heated to 42.degree. C, a hypodiuresis of 54% is produced, and water retention increases the transfer of heat in the organism. Hypodiuresis is brought about by hypersecretion of the antidiuretic hormone (ADH). Such hypersecretion was shown by parallel assays of blood plasma and urine. The same assays also show the extent to which urinary ADH reproduces plasma concentration. The correlation index (between urinary and blood ADH) indicates a certain degree of significance in the role of plasma ADH hypersecretion in hypodiuresis. The latter is also produced by the lowering of glomerular filtration which results from the 47.2% reduction in creatinine clearance. This reduction can be explained by the distribution of the blood mass toward the skin surface of the body. Urinary electrolytes are not changed except for K ion, the increased concentration of which is probably due to the intervention of aldosterone. The study was carried out on 12 human subjects, 20-24 yr old.

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Accession: 005419070



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