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Experimental atherosclerosis of the pulmonary and bronchial arteries

Experimental atherosclerosis of the pulmonary and bronchial arteries

Zhonghua Jie he He Hu Xi Xi Ji Bing Za Zhi 9(3): 136-8 188

ISSN/ISBN: 0253-2689

PMID: 3792146

The atherosclerotic changes of the pulmonary and bronchial arteries in 26 rabbits given high lipid diets were studied. Marked atherosclerosis was found in the pulmonary and bronchial arteries in these experimental animals. It was found that foam cells in the lesions originated mainly from smooth muscle cells and partly from the macrophages. In the lungs we found quite a number of lipophagocytes, the role of which played in the pathogenesis of atherosclerosis was briefly discussed. We suggest that the lesions of pulmonary and bronchial arteries might be used as one of the criteria for the evaluation of the therapeutic effect of drugs on experimental atherosclerosis.

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Accession: 005421848

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