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Experimental intrahepatic portacaval anastomosis: use of expandable Gianturco stents

Radiology 162(2): 481-485
Experimental intrahepatic portacaval anastomosis: use of expandable Gianturco stents
Original Gianturco expandable stents and their modifications were used to create an experimental intrahepatic portacaval anastomosis (EIPCA) in 30 young domestic swine without portal hypertension. The study focused on the design of a suitable stent, the technique of its application, and the evaluation of short-term patency of the EIPCA. A stent with a 2.5-cm-long body and wire skirts on both ends was most suitable for EIPCA creation. Well-positioned stents shunted most of the portal blood in the inferior vena cava circulation and remained patent for 4-6 weeks. Ingrowth of liver parenchyma and abundant proliferation of the intima and connective tissue inside the stent lumen in these rapidly growing animals gradually decreased EIPCA patency, and thrombus formation with diminished blood flow closed them completely.

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Accession: 005424032

PMID: 3797662

DOI: 10.1148/radiology.162.2.3797662

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