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Experimental investigations on the tumorigenic activity of cigarette smoke condensate on mouse skin part 7 comparative studies on condensates from different modified cigarettes



Experimental investigations on the tumorigenic activity of cigarette smoke condensate on mouse skin part 7 comparative studies on condensates from different modified cigarettes



Zeitschrift fuer Krebsforschung und Klinische Onkologie 89(2): 145-152



Condensate from different modified cigarettes were compared with condensate from a standard cigarette with regard to its tumorigenic activity on mouse skin. Significantly lower effects were observed in test series with cigarettes from expanded tobacco. Different results were obtained in experiments with cigarettes from the new smoking materials. In 1 case the effect was higher; in 2 other cases the effect was lower in comparison to the effect of condensate from reference cigarettes. A certain influence may be referred to the diameter of the cigarette, i.e., a thinner cigarette shows a lower biological effect. The lowest tumorigenic effect was observed in tests with cigarettes with a high content of Burley stems.

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