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Experimental morphological study concerning myocardial changes in ethyl alcohol intoxication in the rat

Experimental morphological study concerning myocardial changes in ethyl alcohol intoxication in the rat

Revue Roumaine de Morphologie d'Embryologie et de Physiologie Morphologie et Embryologie 31(1): 51-54

The effects of variable durations of alcohol administration on the myocardium was studied in the white mouse. Light microscopy observations revealed the appearance of steatosis and fuchsinophilia of the myocardium fibers. The intensity of the lesions increased with the duration of the intoxication. Electron microscopic study also revealed progressive changes of the mitochondria, the intracellular junctions as well as the endoplasmic reticulum. The results support a correlation between the observed lesions and the effects of an excess of acetaldehyde.

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