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Experimental neuro leukemia in mice

Experimental neuro leukemia in mice

Eksperimental'naya Onkologiya 3(1): 36-41

The investigation of neuroleukemia in mice with leukemia L-1210 has shown that the main pathologic process is localized in the dura mater of the brain and in the epidural space and dura mater of the spinal cord in the lumbar region. The leukemic cell infiltration into the epidural space and in the dura mater of the brain depends on a direct migration of the leukemia cells from the affected bone marrow of the adjoining vertebrae through the nutrient foramens. The alteration of the epidural space may be a basis for subsequent effects on other divisions of the epidural space and the meninges.

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