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Experimental orbital phyco mycosis in rabbits


Mykosen 24(1): 47-52
Experimental orbital phyco mycosis in rabbits
Spores of Rhizopus oryzae when inoculated into the orbit of healthy rabbits failed to survive for 60 days. Systemic steroids helped establishing an infection as evidenced by proliferating fungi in the retro-orbital tissue, which, however, remained sub-clinical. A mass developed in diabetic rabbits showing proliferating fungus, areas of necrosis and a granulomatous reaction. The fungus was more invasive in acidotic animals as it involved sclera, choroid and episclera. In both cases, the infection remained clinically unmanifested.


Accession: 005424813

PMID: 7231455



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