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Experimental osteo petrosis osteo dysplasia leuko sarcomatosa gallinarum in guinea fowl numida meleagris part 3 passages of the virus and attempts at titration


Obshta i Sravnitelna Patologiya 3: 29-32
Experimental osteo petrosis osteo dysplasia leuko sarcomatosa gallinarum in guinea fowl numida meleagris part 3 passages of the virus and attempts at titration
Eight passages were carried out on 1-2 day old guinea-fowl poults with a local strain Pts-56 of the virus of osteopetrosis (osteodysplasia leucosarcomatosa gallinarum) isolated from a cock. A total of 78% (of 171) of the birds and in most of the experiments up to 100% reacted positively. Continuous viremia existed in the guinea-fowls with manifested osteopetrosis. Infection titer of the virus was 5 .times. 103.75 ID50 in blood collected 360 days p.i. [post-infection]. There was no parallelism between the dose of virus material injected, time of manifestation and the expression of tumor.


Accession: 005424829



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