+ Site Statistics
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on LinkedInFollow on LinkedIn

+ Translate

Experimental pharmacological study of 3 species from genus salvia

Experimental pharmacological study of 3 species from genus salvia

Acta Physiologica et Pharmacologica Bulgarica 10(2): 13-20

Extracts (15) isolated from 3 spp. of genus Salvia were studied: 2 from S. officinalis, 7 from S. triloba and 6 from S. verbenaca. Their effects on the blood pressure of cats and spontaneously hypertensive rats were examined. The smooth-muscle effects of the extracts were studied on isolated segments of guinea pig ileum. The effects of some of the extracts on hexobarbital anesthesia were investigated. Applied i.v. and duodenally, aqueous-alcohol extract of S. officinalis causes moderate, but prolonged, lowering of the blood pressure in cats. Decoction of S. triloba also possesses a similar effect (in experiments on spontaneously hypertensive rats). Most of the extracts isolated from S. officinalis and S. triloba inhibit to various degrees smooth-muscle contractions induced by acetylcholine, histamine, serotonin and BaCl2; extracts of S. verbenaca usually potentiated them. Substances isolated from S. triloba prolong hexobarbital sleep. Future studies of substances isolated from S. officinalis and S. triloba are promising with a view to their spasmolytic and hypotensive actions. There exist marked interspecies differences in the pharmacological effects of biologically active substances isolated from genus Salvia.

(PDF emailed within 1 workday: $29.90)

Accession: 005424948

Download citation: RISBibTeXText

Related references

Experimental pharmacological study of three species from genus Salvia. Acta Physiologica et Pharmacologica Bulgarica 10(2): 13-20, 1984

Chemical compositions of two wild species of the genus Salvia L. from Yugoslavia: Salvia aethiopis and Salvia verticillata. Journal of Essential Oil Research 13(6): 416-418, 2001

Karyological studies on some Salvia L. species of Turkey: II. Salvia viridis L., Salvia glutinosa L., Salvia virgata Jacq., Salvia verbenaca L. Salvia argentea L. Turkish Journal of Botany 17(3): 157-161, 1993

Comparative chemical study of the essential oils of salvia officinalis salvia aucheri salvia verbenaca salvia phlomoides and salvia argentea. Fitoterapia 55(3): 143-148, 1984

Karyological studies on Salvia L. species of Turkey I. Salvia fruticosa Mill., Salvia tomentosa Mill., Salvia officinalis L. Salvia smyrnaea Boiss. (Lamiaceae). Turkish Journal of Botany 17(1): 21-25, 1993

Some kinetic properties of polyphenol oxidase obtained from various Salvia species (Salvia viridis L., Salvia virgata Jacq. and Salvia tomentosa Miller). Food Science and Technology International 9(4): 309-315, 2003

Histological Studies With Histological Key Of The Species Of The Genus Salvia Of Northeastern United States And Adjacent Canada. Iv. Histology Of Leaves Of Salvia Sylvestris L., S. Officinalis L., And S. Pratensis L. American Journal of Pharmacy and the Sciences Supporting Public Health 135: 417-427, 1963

Histological studies with histological key of the species of the genus Salvia of northeastern United States and adjacent Canada HI Histology of flowers of Salvia azurea Lam var grandiflora Benth, S reflexa Hornem, and S urticifolia L. 1963

Cytotaxonomic and phylogenetic study of some Salvia species of the Mediterranean region: the Salvia officinalis L. group. Bulletin de la Societe Botanique de France 123(9): 515-531, 1976

Study of sterility in some forms of Salvia sclarea and other species of Salvia L. 3 ii s"ezd Vses o va genetikov i selektsionerov im N I Vavilova, Leningrad, 16-20 maya 1977 g, 1 Genet i selektsiya rast Tez dokl: 96-97, 1977

Chemical composition of the essential oils of two Salvia species from Iran, Salvia virgata Jacq. and Salvia syriaca L. Flavour and Fragrance Journal 14(1): 45-46, 1999

Chemical composition of the essential oils of two Salvia species from Iran: Salvia verticillata L. and Salvia santolinifolia Boiss. Flavour and Fragrance Journal 14(2): 77-78, 1999

Essential oil composition of two Salvia species from Iran, Salvia nemorosa L. and Salvia reuterana Boiss. Flavour and Fragrance Journal 14(4): 230-232, 1999

Isolation and analysis of bioactive diterpenoids in Salvia species (Salvia chionantha and Salvia kronenburgiii) by micellar electrokinetic capillary chromatography. Journal of Pharmaceutical and Biomedical Analysis 51(2): 439-442, 2010

Supplementary notes on american labiatae d x hyptis caudata d new species hyptis anitae d new species salvia subscandens d new species salvia nubilorum d new species satureja guatemalensis d new species satureja amissa d new species scutellaria modesta d new species scutellaria cylindriflora d new species harlanlewisia sarmentosa d new combination. Brittonia 20(4): 295-313, 1968