+ Site Statistics
+ Resolve Accession
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
Submit PDF Full TextSubmit PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Expression of the troponin complex genes: transcriptional coactivation during myoblast differentiation and independent control in heart and skeletal muscles

, : Expression of the troponin complex genes: transcriptional coactivation during myoblast differentiation and independent control in heart and skeletal muscles. Molecular and Cellular Biology 8(10): 4134-4142

We compared the developmental regulation of the three troponin genes that encode the proteins of the Ca2+ regulatory complex in striated muscles of the Japanese quail. Nuclear run-on transcription and RNA protection analyses showed that the fast skeletal troponin I, the fast skeletal troponin T, and the slow skeletal-cardiac troponin C of genes were transcriptionally coactivated and that transcripts rapidly accumulated within 6 to 12 h after the initiation of myoblast differentiation. The fast-isoform mRNAs of troponin I and troponin T were coexpressed at similar levels in different skeletal muscles, whereas the slow-cardiac troponin C mRNA varied independently and was the only one of these genes expressed in embryonic and adult heart. We conclude that these troponin genes are transcriptionally coactivated during skeletal myoblast differentiation, indicating that their transcription is under precise temporal control. However, this troponin C gene is regulated independently in specialized striated muscles.

(PDF same-day service: $19.90)

Order PDF Full Text


Click here to order any other PDF Full Text

Accession: 005432259

PMID: 3185544

DOI: 10.1128/mcb.8.10.4134

PDF Full Text: Submit

Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:

Other references

Loekman A., 1973: Insecticide resistance in indonesia. Papaevangelou, George J Ninth International Congress on Tropical Medicine And Malaria, Vol Ii Abstracts Of Communications Athens, Greece, October 14-21, 219p Congress Publications Committee: Athens, Greece 208-209

Holman, R.L.; Donnelly, G.L., 1942: Hypoproteinemia As Protection Against Mercuric Chloride Injury In Dogs. Twelve control dogs receiving a single intravenous injection of mercuric chloride, 3.0 mg. per kg., all died within 4 to 11 days afterwards with marked nitrogen retention and extensive necrosis and calcification of the epithelium lining the proxim...

Frumkes, Dr, 2002: The status of the California Rigs-to-Reefs Programme and the need to limit consumptive fishing activities. Planning and policy issues associated with the utilization in California of portions of decommissioned oil platforms as artificial reefs are identified. Problems, solutions, and current progress are discussed. Habitat values of several California...

Digiovanni J.; Singer J.M.; Diamond L., 1984: Comparison of the metabolic activation of 7 12 di methyl benz a anthracene by a human hepatoma cell line hep g 2 and low passage hamster embryo cells. Under similar conditions of cell-mediated mutagenesis, secondary hamster embryo (HE) cells were much more effective than were cells of the human hepatoma cell line, HepG2, in activating 7,12-dimethylbenz(a)anthracene (DMBA) to metabolites mutageni...

Habets, Petra, E. M. H.; Clout, Danielle, E. W.; Deprez, Ronald, H. Lekanne; Van-Roon, Marian, A.; Moorman, Antoon, F. M.; Christoffels, Vincent, M., 2003: Cardiac expression of Ga14 causes cardiomyopathy in a dose-dependent manner. Cardiac expression of a transgene is a common approach for determining the role of gene products in the processes underlying cardiomyopathy and heart failure (HF). We have generated transgenic mice that express the 'harmless' yeast trans...

Dupré, J., 1970: Regulation of the secretions of the pancreas. Carbenoxolone (Biogastrone, Berk) has been shown to reduce the peptic activity and total acidity of gastric juice obtained from anaesthetized pylorus-ligated rats without affecting significantly the volume of gastric juice secreted or the K(+) con...

Anonymous, 2013: Adrenal gland non-Hodgkins lymphoma in a patient with pulmonary adenocarcinoma. Although primary neoplasms of adrenal gland are uncommon, adrenal metastases are frequently encountered in patients with malignancy, and lung is the most common primary tumour site. Among primary tumours of the adrenal gland non-Hodgkin’...

Plaia, M.; Reger, V. A.; Nordgren, G. N., 1998: Anti-stenotic method for occluded and partially occluded arteries. Official Gazette of the United States Patent & Trademark Office Patents 1212(3): 2667-2668, July 21

Iwatsuki, N.; Petersen, O.H., 1978: In vitro action of bombesin on amylase secretion, membrane potential, and membrane resistance in rat and mouse pancreatic acinar cells. A comparison with other secretagogues. Bombesin [an amphibian skin tetradecapeptide] caused depolarization of rat or mouse pancreatic acinar cell membrane, reduction of membrane resistance and a steep rise in amylase output from superfused pancreatic fragments. These effects were simil...

Mathew, Sindhu; Abraham, T. Emilia; Sudheesh, S., 2007: Rapid conversion of ferulic acid to 4-vinyl guaiacol and vanillin metabolites by Debaryomyces hansenii. Debaryomyces hansenii, an isolated yeast strain metabolized ferulic acid to an intermediate compound, namely 4-vinyl guaiacol, by the non oxidative decarboxylation of its side chain. This bioconversion is a highly value added process as 4-vinyl g...