EurekaMag.com logo
+ Site Statistics
References:
52,725,316
Abstracts:
28,411,598
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Expression of transformation in cell hybrids part 2 nonsuppression of the transformed phenotype in hybrids between a chemically transformed and nontransformed derivatives of balb 3t3


Journal of Cellular Physiology 97(2): 147-152
Expression of transformation in cell hybrids part 2 nonsuppression of the transformed phenotype in hybrids between a chemically transformed and nontransformed derivatives of balb 3t3
Hybrid clones derived from a nitrosocarbaryl-transformed Balb/3T3 mouse fibroblast cell line, clone H, and a nontransformed cell line THO2 resemble the transformed parent in clone morphology, higher saturation density, colony formation in medium with reduced serum concentration, growth in agarose and ability to form clones on Balb/3T3 monolayers. Results are discussed in the framework of genetic models which permit or require dominant mutations for the expression of transformed phenotype.


Accession: 005432341



Related references

Expression of transformation in cell hybrids. II. Nonsuppression of the transformed phenotype in hybrids between a chemically transformed and nontransformed derivatives of Balb/3T3. Journal of Cellular Physiology 97(2): 147-152, 1978

Somatic cell hybrids between mouse peritoneal macrophages and sv 40 transformed human cells part 1 positive control of the transformed phenotype by the human chromosome 7 carrying the sv 40 genome. Journal of Experimental Medicine 140(5): 1221-1229, 1974

Suppression and re-expression of transformed phenotype in hybrids of HA-ras-1-transformed rat-1 cells and early-passage rat embryonic fibroblasts. International Journal of Cancer 38(5): 697-705, 1986

Expression of the transformed phenotype in mammalian somatic cell hybrids. Genetics 91(4 PART 2 SUPPL): S53-s54, 1979

Expression of the transformed phenotype and tumorigenicity in somatic cell hybrids. Journal of Cell Science 39: 319-327, 1979

Chromosome patterns of nontransformed variants from chemically transformed Balb-3T3 cells. Journal of Cellular Physiology 83(3): 401-407, 1974

Cytoplasmic microtubules in transformed mouse x nontransformed human cell hybrids: correlation with in vitro growth. Cell 12(1): 319-331, 1977

Lack of intercellular communication between chemically transformed and surrounding nontransformed BALB/c 3T3 cells. Cancer Research 44(11): 5200-5203, 1984

Suppression of the transformed phenotype with retention of the viral 'src' gene in cell hybrids between Rous sarcoma virus-transformed rat cells and untransformed mouse cells. Experimental Cell Research 127(2): 373-384, 1980

Positive control of the transformed phenotype in human hybrids between old normal fibroblasts and sv 40 transformed cells. Federation Proceedingspart 1: 729, 1974