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Expression of virulence factors of bacteria when grown in the presence of subminimum inhibitory concentrations of various antibiotics


, : Expression of virulence factors of bacteria when grown in the presence of subminimum inhibitory concentrations of various antibiotics. Drugs under Experimental & Clinical Research 8(3): 245-250

The ability of a variety of bacteria to elaborate toxins and enzymes was influenced by sub-MIC [minimum inhibitory concentrations] of various antibiotics. Clindamycin prevented the formation of coagulase, .alpha.-hemolysin, DNase and other exotoxins by Staphylococcus aureus in vitro. Such effects were observed in experimental infections in mice with corresponding changes in the host response to the infecting organism. The hemolysin of Escherichia coli was inhibited by streptomycin; the proteases of Pseudomonas aeruginosa were inhibited by tetracycline. The enterotoxin of E. coli and Vibrio cholerae was stimulated by clindamycin; the .beta.-hemolysins of S. aureus and pneumococci were stimulated with sub-MIC of penicillin.

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Troussellier M., 1984: Dynamics of pollution indicator and heterotrophic bacteria in sewage treatment lagoons. The spatio-temporal dynamics of pollution-indicator bacteria and aerobic heterotrophic bacteria were studied in the sewage treatment lagoons of an urban wastewater center after 26 mo. of biweekly sampling at 8 stations in these lagoons. Robust sta...

Gogsadze L.A., 1987: Characteristics of the action of intracellular factors on the growth of chick embryo liver. It is shown that, in the course of development, growth-regulating factors emerge in the chick embryo hepatocytes. With age, a growth-inhibiting function develops in the liver nuclei, and its growth-stimulating counterpart in the cytoplasm.

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Gillum, Richard, F.; Mussolino, Michael, E.; Madans, Jennifer, H., 2001: Fish consumption and hypertension incidence in African Americans and whites: The NHANES I epidemiologic follow-up study. We sought to test the hypothesis that increased consumption of fish is associated with decreased incidence of essential hypertension. Data on fish consumption and incidence of hypertension from a national cohort of 5,394 blacks and whites normoten...

Yudenich, D. M., 1962: The trace elements of honey. Determination of trace elements contained in honey from an apiary located on the eastern slope of the Southern Urals showed that Mo, Cu, and Ti are contained in higher concentrations in the inorganic residue (ash) derived from honey than in the ro...

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Borgaro, Susan, R.; Gierok, Susan; Caples, Heather; Kwasnica, Christina, 2004: Fatigue after brain injury: initial reliability study of the BNI Fatigue Scale. Objective : Fatigue is a common problem of many neurological disorders. Yet, few measures have been developed to adequately assess fatigue, particularly during the early stages following a brain injury. The purpose of this study was to document th...

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