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Exstrophy of the cloacal membrane. A pathologic study of four cases

, : Exstrophy of the cloacal membrane. A pathologic study of four cases. Archives of Pathology & Laboratory Medicine 111(2): 157-160

Exstrophy of the cloaca is a rare congenital anomaly. The authors add the pathologic findings of four distinct cases reported in this article to those reported in the literature. In all cases, common anomalies were recognized. In addition, there were rare anomalies, such as single umbilical artery, vestige of the left superior vena cava, common mesenterium, calcification of the cerebellum, incomplete segmentation of the left lung, abnormal shape of the liver, and knock-knee. The embryology of this complex anomaly is difficult. It is considered that this anomalous condition results from breakdown and mesodermal invasion of the cloacal membrane.

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Accession: 005432531

PMID: 3813831

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Related references

Kaya, H.; Oral, B.; Dittrich, R.; Ozkaya, O., 2000: Prenatal diagnosis of cloacal exstrophy before rupture of the cloacal membrane. We describe a case of cloacal exstrophy what was diagnosed prenatally by ultrasound and confirmed at birth. We also review the literature on 15 previous prenatally diagnosed cloacal extrophy cases.

Langer, J.C.; Brennan, B.; Lappalainen, R.E.; Caco, C.C.; Winthrop, A.L.; Hollenberg, R.D.; Paes, B.A., 1992: Cloacal exstrophy: prenatal diagnosis before rupture of the cloacal membrane. Embryologically, cloacal exstrophy is thought to result from persistence and subsequent rupture of the infraumbilical cloacal membrane during the fifth embryonic week. We report a case of cloacal exstrophy in which a prenatal diagnosis was made pr...

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