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Extended retrograde amnesia gradients peripheral epinephrine and frontal cortex stimulation

, : Extended retrograde amnesia gradients peripheral epinephrine and frontal cortex stimulation. Physiology & Behavior 24(6): 1101-1106

The possibility that hormonal responses to training may increase the susceptibility of memory to an amnestic agent was studied. As long as 1 wk after training, rats that received a s.c. epinephrine injection shortly before electrical stimulation of frontal cortex exhibited amnesia on later retention tests. Apparently retrograde amnesia gradients may reflect maximum susceptibility to amnesia shortly after training because the effects of memory of an amnestic agent are potentiated by the neuroendocrine response to training.

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Accession: 005432667

PMID: 7413789

DOI: 10.1016/0031-9384(80)90054-2

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