+ Site Statistics
+ Resolve Accession
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
Submit PDF Full TextSubmit PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Extended schedule transfer of ethanol discrimination

, : Extended schedule transfer of ethanol discrimination. Pharmacology Biochemistry & Behavior 14(1): 23-26

Stimulus control was established in rats with ethanol (600 mg/kg) and saline by employing a 2-lever response choice task and an FR10 (fixed ratio 10) schedule of food reinforcement. Subjects were then tested with an extended schedule procedure in which lever selection and its perserverance were measured under the training conditions and after the administration of pentobarbital at doses of 2-12 mg/kg. With decreasing doses of pentobarbital, drug-lever selection was observed to decline. The dose at which initial lever selection was evenly distributed between the 2 levers (ED50) was determined to be 4 mg/kg. At this dose the perserverance on the ethanol-appropriate lever was not significantly different than that observed after the training dose of ethanol. The perserverance of saline-lever selection produced by saline was observed to be greater than that produced by the training dose of ethanol on the ethanol-lever. The advantages inherent in employing the extended schedule performance procedure in transfer experiments are discussed.

Order PDF Full Text


Click here to order any other PDF Full Text

Accession: 005432671

PMID: 7465606

DOI: 10.1016/0091-3057(81)90098-8

PDF Full Text: Extended schedule transfer of ethanol discrimination

Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:

Other references

Smith, M.Shane; Bivins Smith, E.R.; Tilley, A.Michael, 2007: Roles of Phosphatidylinositol 3-Kinase and NF-kB in Human Cytomegalovirus-Mediated Monocyte Diapedesis and Adhesion: Strategy for Viral Persistence. Journal of Virology 81(14): 83-94

Jensen, T.; Edwards, J.G., 2012: Calcineurin is required for TRPV1-induced long-term depression of hippocampal interneurons. Transient receptor potential vanilloid 1 (TRPV1) mediates a novel form of presynaptic long-term depression (LTD) in hippocampal interneurons. To date, while TRPV1 is currently being heavily studied in the PNS for its anti-nociceptive and anti-infl...

Van Rompaey Y.K.uranen; Maki; Persoons, 1995: Enhancement and suppression of optical-parametric conversion in the presence of a reflecting boundary. Physical Review. A, Atomic, Molecular, and Optical Physics 51(6): R4349-R4352

Wodarz, D., 2006: Effect of stem cell turnover rates on protection against cancer and aging. Tissue stem cells are responsible for replenishing and maintaining a population of cells which make up a functioning organ. They divide by asymmetric cell division where one daughter remains a stem cell while the other daughter becomes a transit...

Lledó, P.; Johnston, A.; Walker, S.; Pearson, R.M.; Turner, P., 1993: Determination of oxidation phenotype by measurement of propafenone urinary metabolic ratios. Human & Experimental Toxicology 12(2): 161-163

Jordan, J.; Simkins, C.; Corey, G.; Knight, R.; Baker, G. 0., 1952: Uptake and movement of fertilizer phosphorus. The effect of soil moisture tension, and banding and broadcasting of single superphosphate were the variables used in a study of the uptake of soil and fertilizer p by potatoes in the field. The single superphosphate was tagged with p32 and applie...

Anonymous, 1988: The 75th birthday of Aleksandr Iosifovich Popov. Vestnik Moskovskogo Universiteta, Seriya 5: Geografiya 1988(2): 110-111

Burdelya, L.G.; Gleiberman, A.S.; Toshkov, I.; Aygun-Sunar, S.; Bapardekar, M.; Manderscheid-Kern, P.; Bellnier, D.; Krivokrysenko, V.I.; Feinstein, E.; Gudkov, A.V., 2012: Toll-like receptor 5 agonist protects mice from dermatitis and oral mucositis caused by local radiation: implications for head-and-neck cancer radiotherapy. Development of mucositis is a frequent side effect of radiotherapy of patients with head-and-neck cancer. We have recently reported that bacterial flagellin, an agonist of Toll-like receptor 5 (TLR5), can protect rodents and primates from acute ra...

Yang, B.C.; Yang, B.S.; Sung, H.H.; Im, S.K.; Park, S.B.; Chang, W.K.; Lee, C.K., 2002: Studies on the viability of in vitro-matured bovine oocytes vitrified by microdrop and Straw method. To establish vitrification method for bovine oocytes, mature bovine oocytes were vitrified by microdrop (MD) or straw (Straw) method and the viability of vitrified oocytes with or without cumulus cells (CC) were examined by several methods; a) par...

Zamani A., 1979: Contribution to the interpretation of the formation and development of the landforms of Meteora. Annales Geologiques des Pays Helleniques 30(1): 281-290