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Extension of neurites on axons is impaired by antibodies against specific neural cell surface glycoproteins


, : Extension of neurites on axons is impaired by antibodies against specific neural cell surface glycoproteins. Journal of Cell Biology 104(2): 355-362

We have developed an in vitro assay which measures the ability of growth cones to extend on an axonal substrate. Neurite lengths were compared in the presence or absence of monovalent antibodies against specific neural cell surface glycoproteins. Fab fragments of antibodies against the neural cell adhesion molecule, NCAM, have an insignificant effect on the length of neurites elongating on either an axonal substrate or a laminin substrate. Fab fragments of polyclonal antibodies against two new neural cell surface antigens, defined by mAb G4 and mAb F11, decrease the lengths of neurites elongating on an axonal substrate, but have no effect on the lengths of neurites elongating on a laminin substrate. G4 antigen is related to mouse L1, while F11 antigen appears to be distinct from all known neural cell surface glycoproteins. Our results suggest that the G4 and F11 antigens help to promote the extension of growth cones on axons.

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Accession: 005432823

PMID: 3543026

DOI: 10.2307/1612250

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Anonymous, 1962: Annual Report of the Department of Agriculture, Nyasaland Protectorate, for the year 1961/62. In addition to the work mentioned below, varietal trials of maize, barley, sorghum, sugar cane, tobacco, sunflower and groundnut were carried out. . Maize. Data are reported on the degree of tip coverage and percentage of flint grain in 24 varieti...

von Sivers, P., 1973: Untersuchungen uber die Verbreitung von Glossina tachinoides West. und G. morsitans submorsitans New. in der Republik Niger. Zeitschrift angew Ent, 733: 319-326

Kloub, O.; Perry, A.; Tu, P.-Hsien; Lipper, M.; Lope, M.B.atriz, S., 2005: Spindle cell oncocytoma of the adenohypophysis - Report of two recurrent coses. The recently described "spindle cell oncocytoma of the adenohypophysis" is a very rare and often misdiagnosed entity. A benign biologic behavior has been Suggested based on the absence of recurrences with a median follow-up of 3 years. H...

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