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Extension of the transition phenomenon in hen egg white lysozyme ec 3.2.1.17 crystals the case of the monoclinic crystals


, : Extension of the transition phenomenon in hen egg white lysozyme ec 3.2.1.17 crystals the case of the monoclinic crystals. Biochimie (Paris) 60(2): 209-210

In hen egg-white lysozyme (EC 3.2.1.17), a temperature dependent transition was described : the tetragonal crystals (A form) are stable up to 25.degree. C where abruptly they give place to orthorhombic crystals (B form) provided that they are in presence of mother liquor. These new crystals obtained are stable over a broad range of temperature (0-55.degree. C). The phenomenon of conformational transition of the lysozyme molecule which was detected in solution can be exhibited in the solid state: tetragonal and monoclinic crystals obtained at 20.degree. C are both transformed into the same B form which seems to be the stable form at high temperature.

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