EurekaMag.com logo
+ Site Statistics
References:
52,725,316
Abstracts:
28,411,598
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Extensive cross reactivity between Treponema pallidum and cultivable treponemes demonstrated by sequential immunoadsorption


International Archives of Allergy and Applied Immunology 79(3): 282-285
Extensive cross reactivity between Treponema pallidum and cultivable treponemes demonstrated by sequential immunoadsorption
Extensive cross reactivity between Treponema pallidum and three nonpathogenic species of treponemes was demonstrated by the Western blot technique. Rabbit antiserum produced by adjuvant immunization with solubilized T. pallidum antigens reacted with 34 T. pallidum antigens and with approximately 30 antigens each of T. phagedenis biotype Reiter, T. noguchii and T. vincentii. Adsorption of the antiserum with T. phagedenis Reiter removed only about half of the cross-reacting antibodies. Sequential adsorption with all three nonpathogenic treponemes removed antibodies to all but three polypeptides of 36,000, 34,000 and 27,000 daltons.


Accession: 005432947

PMID: 3512456

DOI: 10.1159/000233987



Related references

Genetics of Treponema: relationship between Treponema pallidum and five cultivable treponemes. Journal of Bacteriology 133(1): 101-107, 1978

Genetics of treponema relationship between treponema pallidum and 5 cultivable treponemes. Journal of Bacteriology 133(1): 101-107, 1978

Structure of rrn operons in pathogenic non-cultivable treponemes: sequence but not genomic position of intergenic spacers correlates with classification of Treponema pallidum and Treponema paraluiscuniculi strains. Journal of Medical Microbiology 62(Pt 2): 196-207, 2013

The ultrastructure of cultivable treponemes part 1 treponema phagedenis treponema vicentii and treponema refringens. Acta Pathologica et Microbiologica Scandinavica Section B Microbiology & Immunology 82(3): 329-344, 1974

The ultrastructure of cultivable treponemes part 2 treponema calligyrum treponema minutum and treponema microdentium. Acta Pathologica et Microbiologica Scandinavica Section B Microbiology & Immunology 82(4): 495-507, 1974

Assessment of the cross reactivity between treponema pallidum and borrelia burgdorferi and characterization of the cell immune response to individual treponema pallidum protein antigens in patients with syphilis. Clinical Research 39(2): 499A, 1991

The ultrastructure of cultivable treponemes. 2. Treponema calligyrum, Treponema minutum and Treponema microdentium. Acta Pathologica et Microbiologica Scandinavica. Section B: Microbiology and Immunology 82(4): 495-507, 1974

The ultrastructure of cultivable treponemes. 1. Treponema phagedenis, Treponema vincentii and Treponema refringens. Acta Pathologica et Microbiologica Scandinavica. Section B: Microbiology and Immunology 82(3): 329-344, 1974

Ultrastructural studies of treponemes: location of axial filaments and some dimensions of Treponema pallidum (Nichols strain), Treponema denticola, and Treponema reiteri. Infection and Immunity 7(1): 100-110, 1973

Molecular basis of immunological cross-reactivity between Treponema pallidum and Treponema pertenue. Infection and Immunity 42(2): 634-638, 1983