EurekaMag.com logo
+ Site Statistics
References:
52,725,316
Abstracts:
28,411,598
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Extensive DNA sequence homologies between the human Y and the long arm of the X chromosome


Embo Journal 4(7): 1739-1743
Extensive DNA sequence homologies between the human Y and the long arm of the X chromosome
It has been proposed that sequence homology should exist between the short arms of the human sex chromosomes, in the regions pairing at meiosis. Out of 40 clones picked at random from a collection of non-repetitive DNA sequences derived from the human Y chromosome, we have found nine sequences which show very high homology with sequences located on the X chromosome. All nine probes originate from the euchromatic part of the Y chromosome. All the homologous sequences are located within the Xq12-Xq22-24 region. None of them map to the short arm of the X chromosome. We conclude that an important part of the euchromatic region of the Y chromosome is homologous to the middle of the X chromosome long arm, possibly as a result of recent translation event(s).


Accession: 005432969

PMID: 4029125



Related references

Extensive sequence homologies between Y and other human chromosomes. Journal of Molecular Biology 173(4): 403-417, 1984

Extensive sequence homologies among plant lectins. Federation Proceedings 36(3): 1239, 1977

Extensive sequence homologies among lectins from leguminous plants. Biochemical and Biophysical Research Communications 75(4): 980-986, 1977

Extensive direct-tandem organization of a long repeat DNA sequence on the Y chromosome of chinook salmon. Journal of Molecular Evolution 46(3): 277-287, March, 1998

Extensive amino acid sequence homologies between animal lectins. Proceedings of the National Academy of Sciences of the United States of America 84(18): 6345-6348, 1987

Extensive direct-tandem organization of a long repeat DNA sequence on the Y chromosome of chinook salmon (Oncorhynchus tshawytscha). Journal of Molecular Evolution 46(3): 277-287, 1998

The complete derived amino acid sequence of human lysyl oxidase and assignment of the gene to chromosome 5 (extensive sequence homology with the murine ras recision gene). Matrix 12(3): 242-248, 1992

Two regions of human chromosome 21p share extensive sequence similarity with Y centromere low copy number sequences. American Journal of Human Genetics 61(4 SUPPL ): A391, Oct, 1997

Coordinately regulated flagellar calmodulin and alpha tubulin genes of naegleria share extensive upstream sequence homologies. Journal of Cell Biology 105(4 PART 2): 66A, 1987

DNA sequence analysis reveals extensive homologies of regions preceding hsp70 and alphabeta heat shock genes in Drosophila melanogaster. Proceedings of the National Academy of Sciences of the United States of America 78(10): 6196-6200, 1981